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Repression of cyclin D1 as a target for germ cell tumors
metastatic germ cell tumors cyclin D1
2014/12/12
Metastatic germ cell tumors (GCT) are curable, however GCTs refractory to cisplatin-based chemotherapy have a poor prognosis. This study explores D-type cyclins as molecular targets in GCTs because al...
Effects of Wheat Germ Extract on the Severity and Systemic Symptoms of Primary Dysmenorrhea:A Randomized Controlled Clinical Trial
Dysmenorrhea Herbal Medicines Wheat Germ
2015/10/14
Background: Primary dysmenorrhea is one of the most common disorders in women and the main cause of absenteeism from work and school.
Multiresolution identification of germ layer components in teratomas derived from human, nonhuman primate, and murine embryonic stem cells
stem cell biology Multiresolution germ layer components feature extraction
2009/12/23
Multiresolution identification of germ layer components in teratomas derived from human, nonhuman primate, and murine embryonic stem cells.
Assessment of Piwil2 Gene Expression Pattern upon Germ Cell Development from Mouse Embryonic Stem Cell
Embryonic stem cell Germ cell Embryoid body Piwil2
2015/9/18
Background: In order to improve culture conditions for optimal spermatogenesis, quantitative assessment of the male germ cell gene expression profile upon spontaneous ES cell differentiation is necess...
Mannoprotein Adhesin of Candida albicans Germ Tubes
Candida albicans adhesin germ tube plastic petri dish buccal epithelial cells
2009/7/2
The production and detection of a mannoprotein adhesin (MPA) of the hyphal-form cells of C. albicans on plastic petri dishes was investigated. Using Concanavalin A-coated latex microspheres, the MPA w...
Evidence for inclusion of a segment of Escherichia coli genomic DNA in bovine tooth germ mRNA encoding salivary proline-rich protein P-B
Escherichia coli genomic DNA germ mRNA salivary proline-rich protein P-B
2009/3/3
In the course of cloning of bovine cDNA for proline-rich protein (PRP) P-B from bovine tooth germ cDNA, we found that one clone with 662 bp contained a 5'-terminal 393 bp (1-393 bp) sequence essenti...
Polyamine profiles in rat testis, germ cells and Sertoli cells during testicular maturation
Polyamine profiles rat testis germ cells Sertoli cells
2009/2/23
Polyamine cellular concentrations (putrescine, spermidine and spermine) in the rat testis and testicular cell types were determined by fluorescence spectroscopy of their dansyl derivatives. A met...
Effect of germ cells on vectorial secretion of androgen binding protein and transferrin by immature rat Sertoli cells in vitro
germ cells vectorial secretion androgen binding protein transferrin immature rat Sertoli cells
2009/2/23
The influence of germ cells (greater than 85% pachytene spermatocytes) on vectorial secretion of androgen binding protein (ABP) and transferrin by immature rat Sertoli cells was investigated using t...
Germ cell degeneration in the contralateral testis of the guinea pig with unilateral torsion of the spermatic cord. Quantitative and ultrastructural studies
testis torsion quantitation germ cell guinea pig reproduction
2009/2/23
This study evaluated the long term effects of unilateral torsion of the spermatic cord on the contralateral testis of guinea pigs, employing both fine structural and quantitative studies. Young, adu...
Secretion of androgen binding protein by Sertoli cells is influenced by contact with germ cells
androgen binding protein Sertoli cells germ cells
2009/2/20
Sertoli cells were cultured alone or with germ cells to evaluate the effect of the association with germ cells on the secretory activity of Sertoli cells. Secretion of androgen-binding protein, whic...
Squash preparation studies of germ cells in human fetal testes
testis preleptotene germ cells chromosomes
2009/2/20
Testes from human fetuses 21 to 41 weeks of gestation were investigated using a modified squash technique. At all of the gestational ages examined, 90 to 95% of the germ cells were in interphase. Pr...
Pure Sertoli Cell Cultures：A New Model for the Study of Somatic-Germ Cell Interactions
cell cultures Sertoli cell germ cell
2009/2/19
A new technique involving a brief hypotonic treatment was developed for obtaining pure rat Sertoli cell cultures. This method for the selective removal of the germ cells present in Sertoli cell enri...
Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement
Brown Norway rat accelerated germ cell apoptosis luteinizing hormone replacement
2009/2/18
Reproductive aging in the male Brown Norway (BN) rat is characterized by decreased Leydig cell steroidogenesis associated with seminiferous tubule dysfunction. This could be a result of a combination ...
Contrin, the human homologue of a germ-cell Y-box-binding protein：cloning, expression, and chromosomal localization
human homologue germ-cell Y-box-binding protein chromosomal localization
2009/2/18
Inactivation of germ-cell-specific molecules essential for the production of functional spermatozoa could lead to attractive new means for male contraception. The mouse protein MSY2 is the mammali...
Quantification of apoptotic testicular germ cells in normal and methoxyacetic acid-treated mice as determined by flow cytometry
Spermatogenesis TUNEL
2009/2/18
Several studies have reported the occurrence and significance of programmed cell death (apoptosis) of testicular germ cells in mammals. In those studies, apoptotic germ cells were identified by mo...