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Background: Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been reported to be highly expressed in many tumor tissues, but it is still of value to detect its expression in patients wit...
Background: Multiple sclerosis (MS) is an immune-mediated disease of polygenic etiology. Tumor necrosis factor-α (TNF-α) microsatellite as a proinflammatory cytokine is believed to play an important r...
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Background:: Preeclampsia is the most common serious disorder during pregnancy and studies show several immune-related processes in its pathophysiology. The role of cytokines and their expression rema...
cMethods: One hundred and ninety-six patients with brucellosis and 81 healthy farmers (controls) who owned infected animals and consumed their contaminated dairy products were included in this study. ...
Monoclonal antibodies have already established a secure position as a very promising strategy for anti-tumor therapeutics. High specificity and high affinity are attractive characteristics of antibodi...
This study was carried out to assess the role of tumor necrosis factor (TNF-a) and interleukin-6 (IL-6 ) in plasma and peritoneal fluid in higher rates of adhesion formation following standard bowel i...
The aim of this study was to develop a human tumor necrosis factor alpha (hTNF-a) ELISA system because specific and sensitive measurement of low levels of circulating TNF-a is very important for enlig...
Schistosomiasis is estimated to affect more than 200 million people especially in rural and agricultural areas. Schistosoma haematobium causes significant urinary tract diseases and is mediated by T c...
Immunotoxicity is one of toxic effects of dibutyltin(DBT)compounds. In our previous study, the inhibitory effects of DBT on the productions of tumor necrosis a(TNFα)and interleukin-1β in a murine macr...
We have evaluated the effect of natural human interferon (IFN)-α on the growth of chlamydia trachomatis in human epithelial cells in vitro and revealed that IFN-α has reduced both growth and infecti...
Tumor necrosis factor (TNF alpha) is present in elevated levels in peritoneal fluid from infertile women with endometriosis. The effect of TNF alpha on human sperm motility in vitro was evaluated ...
It was recently observed that treatment of patients with a high dosage of human interleukin (IL-2) resulted in suppression of plasma concentrations of testosterone. A murine model was developed to a...
Whether cytokines present in human peritoneal fluid reduce sperm motility, and thus contribute to infertility, is investigated. The human recombinant cytokines, tumor necrosis factor-alpha, interl...
The actions of two cytokines, tumor necrosis factor (TNF) and interleukin-1 (IL-1), on testosterone production by dispersed adult testis cells and purified Leydig cells in culture were studied. In o...

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