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First Report on Isolation and Characterization of Leishmania major from Meriones hurrianae (Rodentia: Gerbillidae) of A Rural Cutaneous leishmaniasis Focus in South-Eastern Iran
Meriones hurrianae Leishmania major Molecular Characterization RAPD-PCR Reservoir Host Iran
2015/10/8
Background: Zoonotic Cutaneous Leishmaniasis (ZCL) is an endemic health problem in many rural areas of Iran, with doubled number of incidences over the last decade. Different species of rodents serve ...
Live logarithmic phase Promastigotes of Leishmania major induced high level of INF-γ but lower level of IL-10 in whole blood culture of healthy individuals
Human Logarithmic Metacyclic Axenic amastigotes
2009/12/30
Stage-specifci developmental forms of Lesihmania major promastigotes were grown in vitro. Procyclic and metacyclic promastigotes were cultured and separated by peanut agglutinin. The axenic amastigote...
RELIMINARY STUDIES OF THE EFFECT OF LAVAMISOLE ON THE IMMUNE RESPONSE OF MICE INFECTED WITH LEISHMANIA
LAVAMISOLE IMMUNE RESPONSE MICE INFECTED LEISHMANIA
2009/12/30
The susceptibility of various strains of mice to infection by Leishmania tropica (major) was recently studied in this laboratory. The infection in A/J, C3H, CBA, AKR/J, AKR/CU, and C57B1 mice (the sem...
Detection of Leishmania major In Naturally Infected Sand Flies Using Semi Nested-PCR
Leishmania major Sand fly Leishmaniasis PCR Iran
2009/12/17
Background: The aim of this study was to assess Leishmania infection in sand fly species from areas where leishmaniasis is endemic. This is important for prediction of the risk and expansion of the di...
Flow Cytometric Analysis of Leishmania Reactive CD4+/CD8+ Lymphocyte Proliferation in Cutaneous Leishmaniasis
CFSE CD4+/CD8+ T cells Proliferation Cutaneous leishmaniasis
2009/12/17
Background: Determination of the division history of T cells in vitro is helpful in the study of effector mechanisms against infections. Technique described here uses the intracellular fluorescent lab...
Pathogenicity Variations of Susceptibility and Resistance to Leishmania major MRHO/IR/75/ER Strain in BALB/c and C57BL/6 mice
Balb/c C57bl/6 Pathogenicity Iran Leishmania major MRHO/IR/75/ER
2009/12/16
Background: To compare the pathogenicity differences in two susceptible Balb/c and resistant C57bl/6 mice infected with Leishmania major MRHO/IR/75/ER as a prevalent strain of zoonotic cutaneous leish...
The Effect of Alkanna tincturia and Peganum harmala Extracts on Leishmania major (MRHO/IR/75/ER) in vitro
Leishmania major Peganum harmala Alkanna tincturia In-vitro
2009/12/14
Background: Cutaneous leishmaniasis is an important health problem caused by Leishmania spp. As there is no vaccine, drug treatment is the only way to tackle leishmaniasis. In the present study, inhib...
Effect of Methanolic Extracts of Artemisia aucheri and Camellia sinensis on Leishmania major (In Vitro)
Leishmania Artemisia aucheri Camellia sinensis medicinal plant promastigote
2009/6/19
Aim: Infections caused by protozoa of the genus Leishmania are major worldwide health problems with high endemicity in developing countries. The incidence of leishmaniasis has increased in the absence...
Hyperbaric hyperoxia enhances the lethal effects of amphotericin B in Leishmania braziliensis panamensis
hyperbaric human oxygen toxicity drug
2009/6/12
Leishmania braziliensis panamensis promastigotes were exposed in vitro to amphotericin B (AmB), menadione, or phenazine methosulfate under normoxic conditions. Promastigotes were also exposed to hyper...
Hypoxia and Amphotericin B - induced Killing of Leishmania braziliensis panamensis and Candida albicans
Hypoxia Amphotericin B Leishmania braziliensis panamensis Candida albicans
2009/5/8
Muhvich KH, Anderson LH, Wilson B, Howard RT, Mehm WJ. Hypoxia and Amphotericin B - induced Killing of Leishmania braziliensis panamensis and Candida albicans. J. Hyperbaric Med 1992; 7(4):199-206.
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Hyperbaric hyperoxia enhances the lethal effects of amphotericin B in Leishmania braziliensis panamensis
hyperbaric human oxygen toxicity drug
2009/3/28
Leishmania braziliensis panamensis promastigotes were exposed in vitro to amphotericin B (AmB), menadione, or phenazine methosulfate under normoxic conditions. Promastigotes were also exposed to hyper...
Morphological and molecular studies on Sri Lankan Leishmania
Sri Lankan Leishmania cytochrome b gene
2010/12/10
Cutaneous leishmaniasis (CL) is an emerging disease in Sri Lanka, more than 400 cases having been reported since 2001. However, the morphology and taxonomic status of the Sri Lankan strain of Leishman...
Preparation of a K39sub Recombinant Antigen for the Detection of Leishmania infantum Antibodies in Human: a Comparative Study with an Immunochromatographic Test and Direct Agglu-tina¬tion
K39sub Antigen Commercial dipstick rk39 Human visceral leishmani¬ asis
2010/4/9
Background: The Mediterranean type of kala-azar is occurred in different parts of Iran and caused by Leishmania infan¬tum. A rapid and valid test for early detection of visceral leishmaniasis in h...
Preparation of a K39sub Recombinant Antigen for the Detection of Leishmania infantum Antibodies in Human: a Comparative Study with an Immunochromatographic Test and Direct Agglu-tina¬tion
K39sub Antigen Commercial dipstick rk39 Human visceral leishmani¬ asis
2010/4/9
Background: The Mediterranean type of kala-azar is occurred in different parts of Iran and caused by Leishmania infan¬tum. A rapid and valid test for early detection of visceral leishmaniasis in h...
Immunological Effects of Leishmania major Secretory and Excre¬tory Products on Cutaneous Leishmaniasis in BALB/c Mice
Excretory-Secretory proteins Balb/C Acetylcholinesterase
2010/4/9
Background: To evaluate the immunological properties of Leishmania major excreted- secreted (E-S) products on the progress of leishmaniasis in susceptible BALB/c mice. Methods: Promastigotes of the Le...