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Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development. However, for the vast majority of those mutations, researchers are unsure of how they contribute to...
The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their “plasticity,” or ability to change those connections when new i...
Study reveals how collapse of protein processes is driver of aging and death（图）
Study reveals collapse protein processes driver aging and death
2019/10/28
Cells undergo natural aging and death, processes that impact a multitude of cellular factors. A new Stony Brook University-led study published in Proceedings of the National Academy of Sciences (PNAS)...
Study shows limitations of method for determining protein structure（图）
Study limitation determine protein structure
2019/10/17
A new study by chemists at the University of Arkansas shows that X-ray crystallography, the standard method for determining the structure of proteins, may provide inaccurate information about a critic...
Under the watchful eyes of five high-speed cameras, a small bird named Gary waits for the signal to fly. Diana Chin, a researcher at Stanford University and Gary's trainer, points her finger to a perc...
Study of LGB gene polymorphisms of small ruminants reared in Eastern Europe
β-LG sheep goats milk production Hungary
2018/11/23
The objectives of the current research were: (i) to determine the allele and genotype frequencies of the LGB gene in the sheep and goat breeds reared in Eastern Europe; (ii) to implement a comparative...
Study reveals the multitasking secrets of an RNA-binding protein
multitasking secrets RNA-binding protein
2017/4/27
Researchers from Princeton University and the National Institute of Environmental Health Sciences have discovered how a fruit fly protein binds and regulates two different types of RNA target sequence...
New genetic engineering technique could help design,study biological systems
New genetic engineering technique design study biological systems
2017/2/16
A new technique will help biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines, modify crops to grow with limited water or study the effects of a ...
Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study
BMI children genetics international comparisons twins
2018/12/3
Background: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking.
A year and a half ago, researchers at Brown University found a molecular gas pedal for melanin production. Now they’ve found a brake. For scientists, the finding deepens not only the basic understandi...
Gene editing study reveals possible 'Achilles heel' of sickle cell disease
Gene editing study Achilles heel sickle cell disease
2015/9/25
Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell d...
Many Experiments for the Price of One:A Breakthrough in the Study of Gene Regulation
Price of One Gene Regulation
2015/6/18
Inside every cell that makes up a diminutive fruit fly is a vast, dynamic network of information—the genome whose ~15,000 genes allow that cell to function. In a study recently published as a Br...
Porcine perilipin (PLIN) gene: Structure, polymorphism and association study in Large White pigs
pig perilipin polymorphism
2015/6/8
Perilipin, encoded by the PLIN gene, is a lipid droplet-associated phosphoprotein that functions as a key regulator of triacylglycerol storage and hydrolysis in adipocytes. In this study, structure an...
Discovery laboratories are dealing with DNA sequencer-based technologies which have seen great advancement over the past decade, resulting in several steps of the genotyping process becoming automated...
Researchers develop models to study polyelectrolytes, including DNA and RNA（图）
DNA RNA polyelectrolytes
2014/8/26
Researchers from North Carolina State University have developed a novel and versatile modeling strategy to simulate polyelectrolyte systems. The model has applications for creating new materials as we...