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Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi
arachidonic acid carnitine dehydroepiandrosterone docosahexaenoic acid malnutrition pregnenolone sulfate stunting
2018/11/21
Background: Stunting affects ～25% of children <5 y of age and is associated with impaired cognitive and motor development and increased morbidity and mortality. The pathogenesis of stunting is poorly ...
Comparison of midupper arm circumference and weight-for-height z score for assessing acute malnutrition in Bangladeshi children aged 6–60 mo: an analytical study
community-based management of acute malnutrition detection of malnutrition in children aged <5 y midupper arm circumference wasting weight-for-height z score
2018/11/20
Background: In clinical settings, wasting in childhood has primarily been assessed with the use of a weight-for-height z score (WHZ), and in community settings, it has been assessed via the midupper a...
Moderate-to-vigorous physical activity, but not sedentary time, predicts changes in cardiometabolic risk factors in 10-y-old children: the Active Smarter Kids Study
physical activity sedentary time cardiometabolic risk factors
2018/11/16
Recently, Skrede et al. (1) prospectively examined the association of objectively measured sedentary time and subcomponents of physical activity with individual and clustered cardiometabolic risk fact...
Effect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster-randomized trial
moderate acute malnutrition ready-to-use supplementary food relapse supplemental feeding program sustained recovery wasting
2018/11/15
Background: Children who recover from moderate acute malnutrition (MAM) have high rates of relapse in the year after nutritional recovery. Interventions to decrease these adverse outcomes are needed t...
Follow-up of a randomized trial on postdischarge nutrition in preterm-born children at age 8 y
preterm-born infants postdischarge nutrition follow-up growth body composition bone metabolic health
2018/11/15
Background: Early nutritional interventions may modulate health risks in preterm-born infants. Previously, we showed that preterm-born infants fed an isocaloric protein- and mineral-enriched postdisch...
A micronutrient-fortified young-child formula improves the iron and vitamin D status of healthy young European children: a randomized, double-blind controlled trial
iron deficiency vitamin D deficiency cow milk young-child formula vitamin D supplements micronutrient fortification young children
2018/11/12
Background: Iron deficiency (ID) and vitamin D deficiency (VDD) are common among young European children because of low dietary intakes and low compliance to vitamin D supplementation policies. Milk i...
Nonviolent civil insecurity is negatively associated with subsequent height-for-age in children aged <5 y born between 1998 and 2014 in rural areas of Africa
civil insecurity stunting Africa community and international nutrition height-for-age
2018/11/12
Background: Civil wars and wars between states have occurred less frequently since the start of the 21st century, but civil insecurity outside the contexts of official wars continues to plague many pa...
What does it mean to target specific serum 25-hydroxyvitamin D concentrations in children and adolescents?
serum 25-hydroxyvitamin children adolescents
2018/12/18
The task of determining dietary requirements for vitamin D intake is one of the key unresolved issues in vitamin- and mineral-related nutrition. The complexities of issues, including determining intak...
Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial
NaFeEDTA cognition fortification iron lead
2018/12/18
Background: Lead is a common neurotoxicant and its absorption may be increased in iron deficiency (ID). Thus, iron fortification to prevent ID in populations is a promising lead mitigation strategy. T...
Estimation of the dietary requirement for vitamin D in white children aged 4–8 y: a randomized, controlled, dose-response trial
children dose-response ODIN randomized controlled trial recommendations requirement vitamin D
2018/12/18
Background: Children in northern latitudes are at high risk of vitamin D deficiency during winter because of negligible dermal vitamin D3 production. However, to our knowledge, the dietary requirement...
Mortality in children with complicated severe acute malnutrition is related to intestinal and systemic inflammation: an observational cohort study
cytokines diarrhea inflammation inflammatory bowel disease severe acute malnutrition
2018/12/18
Background: Diarrhea affects a large proportion of children with severe acute malnutrition (SAM). However, its etiology and clinical consequences remain unclear.
Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study
fatty acid cholesteryl ester phospholipid desaturase elongase intervention diet physical activity children
2018/12/14
Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited.
Effect of a 2-y dietary and physical activity intervention on plasma fatty acid composition and estimated desaturase and elongase activities in children: the Physical Activity and Nutrition in Children Study
fatty acid cholesteryl ester phospholipid desaturase elongase intervention diet physical activity children
2018/12/18
Background: Evidence on the effects of lifestyle interventions on plasma fatty acid composition in children is limited.
Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial
lipid-based nutrient supplements child growth home fortification multiple micronutrients supplementation
2018/12/14
Background: Childhood stunting usually begins in utero and continues after birth; therefore, its reduction must involve actions across different stages of early life.
The association of serum choline with linear growth failure in young children from rural Malawi
betaine children choline linear growth malnutrition trimethylene-N-oxide stunting undernutrition
2018/12/3
Background: Choline is an essential nutrient for cell structure, cell signaling, neurotransmission, lipid transport, and bone formation. Choline can be irreversibly converted to betaine, a major sourc...