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Background: Cocoa flavanol intake, especially that of (−)-epicatechin, has been linked to beneficial effects on human cardiovascular function. However, cocoa also contains the methylxanthines th...
Background: Many trials assessing effects of dietary weight loss on vascular function have been performed without no–weight loss control groups and in individuals with obesity-related morbidities. Usu...
Background: Cardiovascular diseases (CVDs) are the greatest cause of death globally, and their reduction is a key public-health target. High blood pressure (BP) affects 1 in 3 people in the United Kin...
Background: Clinicians often recommend limiting caffeine intake while attempting to conceive; however, few studies have evaluated the associations between caffeine exposure and menstrual cycle functio...
Background: Daily consumption of Concord grape juice (CGJ) over 3–4 mo has been shown to improve memory function in adults with mild cognitive impairment and reduce blood pressure in hypertensive adul...
Carbohydrates (CHOs), branched-chain amino acids (BCAAs) and caffeine are known to improve running performance. However, no information is available on the effects of a combination of these ingredien...
Obesity increases cardiovascular disease risk and is associated with factors of the “metabolic syndrome” (MetS), a disorder including hypertension, hypercholesterolemia and/or impaired glucose toleran...
A hypothesis was tested that a reaction product between superoxide (O2  ) and nitric oxide (NO) mediates post-ischemic coronary endothelial dysfunction that ischemic preconditioning (IPC) protects...
Calcineurin: Form and Function     Calcineurin  Form  Function       2014/3/31
The year 1999 marked the 20th anniversary of the isolation of the Ca 21- and calmodulin-dependent protein serine/threonine phosphatase calcineurin (206). During the past 20 years, the biological roles...
Phosphoinositide-specific phospholipase C (PLC) isozymes found in eukaryotes comprise a related group of proteins that cleave the polar head group from inositol phospholipids. Under the control of ce...
Corpora (bodies) lutea (yellow) were named by Marcello Malpighi (1628 –1694) and first accurately described by Regnier de Graaf (1641–1673) who noted that after coitus “globular bodies” appeared on th...
Animal and human studies have documented several effects of different dietary and tissue concentrations of long-chain polyunsaturated fatty acids (LCPUFAs) on retinal function and vision. The enhan...

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