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Probing the Structure of Supported Membranes and Tethered Oligonucleotides by Fluorescence Interference Contrast Microscopy
Water Oligonucleotides Microscopy, Fluorescence Microscopy, Interference Membranes, Artificial Sensitivity and Specificity Surface Properties Models, Chemical Silicon Dioxide
2016/5/24
Fluorescence interference contrast microscopy (FLIC) is a powerful method to structurally characterize fluorescent objects with nanometer-scale resolution in the z direction. Here we use FLIC to chara...
Hippocampal Context Processing is Critical for Interference Free Recall of Odor Memories in Rats
hippocampus context interference
2015/8/7
Interference is a critical problem for memory systems and a primary cause of retrieval failure. One strategy for minimizing interference is to associate the items to be remembered with the context in ...
Studies of the complex of ribosomal protein L1 with its binding site in 23S rRNA: Modification -interference, mutagenesis and crosslinking
Ribosomal proteins escherichia coli ribosomes the protein spiral protein
2014/12/11
Interaction of ribosomal protein L1 and the 23S rRNA plays an important role in both the structure and biological activity of the Escherichia coli ribosome. We have minimized the binding site for prot...
Validation of Gene Silencing Using RNA Interference in Buffalo Granulosa Cells
RNAi Transfection CYP19 Gene 17beta- Estradiol Buffalo Transcript Abundance
2016/5/9
Silencing of a specific gene using RNAi (RNA interference) is a valuable tool for functional analysis of a target gene. However, information on RNAi for analysis of gene function in farm animals is re...
Targeted Suppression of Connexin 43 in Ovine Preimplantation Embryos by RNA Interference Using Long Double-stranded RNA
Connexin 43 RNA Interference Ovine Embryo
2016/5/4
RNA interference (RNAi) is an acknowledged useful and effective tool to study gene function in various cells. Here, we suppressed the Connexin 43 (Cx 43) gene expression during in vitro development of...
Interference Competition between Rails and Crakes (Rallidae) during Foraging in the Post-Breeding Season
Rallidae Water Rail Rallus aquaticus Crake Porzana interaction aggressive behavior
2010/3/26
In an old riverbed of the Tigris River near the city of Diyarbakir (SE Turkey), observations of foraging Rallidae were made in October 2004. Reciprocal reactions (aggression, mutual foraging) were not...
![](http://www.firstlight.cn/upload/imgfile/20101/11/2010111145340.jpg)
Ever since RNA interference was discovered, in 1998, scientists have been pursuing the tantalizing ability to shut off any gene in the body — in particular, malfunctioning genes that cause diseases su...
RNA干涉及其应用前景RNA Interference and Its Promising Future
RNA干涉 小干涉RNA 转录后基因沉默 Dicer酶 RdRP活性 功能基因组
2007/12/30
摘要RNA干涉是指由特定双链RNA(dsRNA)引起的转录后基因沉默现象。研究表明,Dicer断裂dsRNA产生的小干涉RNA可以抑制哺乳动物体细胞和胚胎中的基因的表达。 RdRP在扩增RNAi中起着关键性的作用,RdRP活性复制较长的触发性dsRNA或以一种非引物的方式复制短的siRNA,即以siRNA为引物的RdRP反应使靶mRNA转变为dsRNA,同时复制触发性dsRNA。 所有的产物又可作...
摘要RNAi是多种生物体内由dsRNA介导的同源mRNA降解现象。这是一个高度特异化的过程,涉及多种蛋白质的共同参与。在这一过程中,siRNA的结构影响其两条链装配到RISC中去的能力。除了与RISC结合外,siRNA还引导了RITS复合物结合到同源染色质,介导异染色质化过程。干扰效应的扩散,即系统性沉默可能依赖于跨膜蛋白的转运,并且很可能是在多因素调控下完成的。Abstract: RNA int...
专著信息
书名
Interference effect of epigallocatechin-3-gallate on targets of nuclear factor κB signal transduction pathways activates by EB virus encoded latent memebrane protein 1.
语种
英文
撰写或编译
作者
Zhao Yan...
Interference Competition between Rails and Crakes (Rallidae) during Foraging in the Post-Breeding Season
Rallidae Water Rail Rallus aquaticus Crake Porzana interaction aggressive behavior
2010/3/26
In an old riverbed of the Tigris River near the city of Diyarbakir (SE Turkey), observations of foraging Rallidae were made in October 2004. Reciprocal reactions (aggression, mutual foraging) were not...