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Therapeutic brain modulation with targeted large neutral amino acid supplements in the Pah-enu2 phenylketonuria mouse model
phenylketonuria inborn error of metabolism large neutral amino acids mouse model neurotransmitters brain biochemistry treatment
2018/12/18
Background: Phenylketonuria treatment consists mainly of a Phe-restricted diet, which leads to suboptimal neurocognitive and psychosocial outcomes. Supplementation of large neutral amino acids (LNAAs)...
Probing Protein Electrostatics with a Synthetic Fluorescent Amino Acid
pteropod aragonite flux East Sea (Sea of Japan)
2016/5/24
Electrostatics affect virtually all aspects of protein structure and activity and are particularly important in proteins whose primary function is to stabilize charge. Here we introduce a fluorescent ...
Mg Coordination by Amino Acid Side Chains is Not Required for Assembly and Function of the Special Pair in Bacterial Photosynthetic Reaction Centers
Amino Acids Fourier Analysis Light-Harvesting Protein Complexes Magnesium xidation-Reduction Photosynthetic Reaction Center Complex Proteins Spectrometry,Fluorescence Spectrum Analysis, Raman
2016/5/23
A conserved histidine serves as the axial ligand to the Mg of bacteriochlorophylls in the photosynthetic reaction center (RC) and many other photosynthetic systems. The histidine axial ligands to each...
Chlorophyll-Amino Acid Interactions in Synthetic Models
Chlorophyll Amino Acid Interactions Synthetic Models
2016/5/20
A number of amino acids and molecules ofrelated functionality have been covalently connected to pyrochlorophyllide a (PCbla) and bacteriopyrochlorophyllide a (BPCbla) to determine their impact on the ...
Effect of L- or DL-methionine Supplementation on Nitrogen Retention, Serum Amino Acid Concentrations and Blood Metabolites Profile in Starter Pigs
Amino Acids Profile Methionine Pigs Nitrogen Balance
2016/5/20
The objective of the current study was to evaluate the effect of supplementation of either L-methionine (L-Met) or DL-methionine (DL-Met) to diets of starter pigs on nitrogen (N) balance, metabolism, ...
Effects of Rice Bran, Flax Seed, and Sunflower Seed on Growth Performance, Carcass Characteristics, Fatty Acid Composition, Free Amino Acid and Peptide Contents, and Sensory Evaluations of Native Korean Cattle (Hanwoo)
Flax Seed Methionine Glutamic Acid α-Aminoadipic Acid Sensory Evaluations Hanwoo
2016/5/19
This study was conducted to evaluate the effect of dietary supplementation with rice bran, flax seed, or sunflower seed to finishing native Korean cattle (Hanwoo) on growth performances, carcass chara...
Early nutritional support for extremely premature infants: what amino acid amount should be given?
nutritional extremely premature infants amino acid amount
2018/11/30
Consistently providing adequate nutrition to extremely preterm infants remains a clinical challenge. This is especially true in early postnatal life, when support is largely dependent on parenteral nu...
Serum aminotransferases in nonalcoholic fatty liver disease are a signature of liver metabolic perturbations at the amino acid and Krebs cycle level
fatty liver gene expression liver injury metabolomics transaminases
2018/11/27
Background: Extensive epidemiologic studies have shown that cardiovascular disease and the metabolic syndrome (MetS) are associated with serum concentrations of liver enzymes; however, fundamental cha...
福建师范大学生命科学学院生物化学英文课件 Amino acid metabolism。
Integration of general amino acid control and TOR regulatory pathways in yeast
GCN4 GCN2 TOR
2015/5/25
Two important nutrient sensing and regulatory pathways, the general amino acid control (GAAC) and the target of rapamycin (TOR), participate in the control of yeast growth and metabolism in response t...
Design, Synthesis and Study of DNA-Targeted Benzimidazole-Amino Acid Conjugates
DNA minor groove Benzimidazole Amidine
2015/5/21
The DNA minor groove continues to be an important biological target in the development of anticancer, antiviral, and antimicrobial compounds. Among agents that target the minor groove, studies of well...
Comparison of Carcass and Sensory Traits and Free Amino Acid Contents among Quality Grades in Loin and Rump of Korean Cattle Steer
Korean Cattle Steers Carcass Traits Quality Grades Loin Rump
2016/5/19
This study was performed to compare carcass traits, sensory characteristics, physiochemical composition, and contents of nucleotides, collagen, and free amino acids among quality grades (QG) and to un...
Determination and Prediction of the Amino Acid Digestibility of Sunflower Seed Meals in Growing Pigs
Chemical Composition Amino Acid Digestibility Growing Pigs Prediction Equations
2016/5/17
This experiment was conducted to evaluate the chemical composition and amino acid (AA) digestibility of sunflower seed meal (SFSM) and to use this data to develop prediction equations for estimating A...
In Vivo Labeling Of A Model β-Clam Protein With A Fluorescent Amino Acid
nonsense suppression technique L-(7-hydroxycoumarin-4-yl) ethyl glycine unnatural amino acid CRABP I
2014/12/12
Proteins can be labeled with different tags to enable their structural and functional investigations. In addition, labeling proteins at specific sites helps in studying the conformational dynamics of ...
Effects of amino acid substitution on chain packing in genetically engineered periodic polypeptides
Polymer materials biological protein protein polymers tyrosine crystal cell protein e. coli
2014/12/11
Architecturally well-defined polymeric materials with precisely controlled chain length, sequence, stereochemistry and interchain interactions can be produced using the fidelity of biological protein ...